Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 17/20 | 0.64 |
| ▸ | NPC1 | O15118 | 16/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 5/20 | 0.61 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28921534 | 1.00 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL16688465 | 0.78 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL17131826 | 0.76 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL7451695 | 0.76 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL12830045 | 0.75 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL5866982 | 0.75 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL353911 | 0.75 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL16688497 | 0.74 | RAB9A (0.78) | RAB9ANPC1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL7963500 | 0.74 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL23143761 | 0.73 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536646-A | Nematicidal active compound and preparation method and application thereof | 华东理工大学 | 2022-12-30 | — | — | CN | disclosed |