Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 3/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29848069 | 0.83 | MAPT (1.00) | NPC1MAPTSMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL657181 | 0.81 | RAB9A (0.70) | NPC1MAPTSMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL22777752 | 0.78 | PIM1 (0.71) | MAPTPIM1PIM2PTPN22TSHR | |
| SCHEMBL5393443 | 0.78 | PIM1 (0.71) | MAPTPIM1PIM2PTPN22TSHR | |
| SCHEMBL29448008 | 0.78 | PIM1 (0.71) | MAPTPIM1PIM2PTPN22TSHR | |
| SCHEMBL11687990 | 0.76 | GAA (0.61) | NPC1MAPTSMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL6269928 | 0.71 | GSTA1 (0.62) | MAPTALOX15HPGDSHDAC3HDAC1 | |
| SCHEMBL11109735 | 0.70 | NPC1 (0.81) | NPC1MAPTSMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL11446228 | 0.69 | MAPT (0.54) | NPC1MAPTRAB9AMAPK1NPSR1 | |
| SCHEMBL11535994 | 0.69 | MAPT (0.53) | NPC1MAPTSMN1; SMN2RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536646-A | Nematicidal active compound and preparation method and application thereof | 华东理工大学 | 2022-12-30 | — | — | CN | disclosed |