SCHEMBL30100837

SCHEMBL30100837

Cc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RARB P10826 20/20 1.00
RARG P13631 19/20 1.00
RARA P10276 18/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346037 1.00 RARB (1.00) RARBRARGRARA
SCHEMBL7642585 0.91 RARB (0.84) RARBRARGRARA
SCHEMBL6234641 0.91 RARB (1.00) RARBRARGRARA
SCHEMBL6232868 0.91 RARB (1.00) RARBRARGRARA
SCHEMBL6210444 0.91 RARA (1.00) RARBRARGRARA
SCHEMBL6233323 0.90 RARB (1.00) RARBRARGRARA
SCHEMBL8472049 0.90 RARB (1.00) RARBRARGRARA
SCHEMBL31725103 0.89 RARB (0.80) RARBRARGRARA
SCHEMBL6237239 0.88 RARB (1.00) RARBRARGRARA
SCHEMBL6236971 0.88 RARB (1.00) RARBRARGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347795-A1 METHODS TO GENERATE MACULAR, CENTRAL AND PERIPHERAL RETINAL PIGMENT EPITHELIAL CELLS The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2024-04-10 EP disclosed
EP-4346928-A1 BIODEGRADABLE TISSUE SCAFFOLD WITH SECONDARY MATRIX TO HOST WEAKLY ADHERENT CELLS The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2024-04-10 EP disclosed
WO-2022251477-A1 BIODEGRADABLE TISSUE SCAFFOLD WITH SECONDARY MATRIX TO HOST WEAKLY ADHERENT CELLS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-12-01 WO disclosed
WO-2022251499-A1 METHODS TO GENERATE MACULAR, CENTRAL AND PERIPHERAL RETINAL PIGMENT EPITHELIAL CELLS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-12-01 WO disclosed