SCHEMBL346037

SCHEMBL346037

Cc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RARB P10826 20/20 1.00
RARG P13631 19/20 1.00
RARA P10276 18/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30100837 1.00 RARB (1.00) RARBRARGRARA
SCHEMBL7642585 0.91 RARB (0.84) RARBRARGRARA
SCHEMBL6234641 0.91 RARB (1.00) RARBRARGRARA
SCHEMBL6232868 0.91 RARB (1.00) RARBRARGRARA
SCHEMBL6210444 0.91 RARA (1.00) RARBRARGRARA
SCHEMBL6233323 0.90 RARB (1.00) RARBRARGRARA
SCHEMBL8472049 0.90 RARB (1.00) RARBRARGRARA
SCHEMBL31725103 0.89 RARB (0.80) RARBRARGRARA
SCHEMBL6237239 0.88 RARB (1.00) RARBRARGRARA
SCHEMBL6236971 0.88 RARB (1.00) RARBRARGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034081-A1 COMPOSITIONS AND METHODS RELATED TO INHIBITION OF ADENOMAS AND ADENOCARCINOMAS UNIV COLUMBIA (US) 2026-02-05 US claimed
EP-4569090-A2 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS Trailhead Biosystems Inc. (US) 2025-06-18 EP claimed
EP-4558622-A1 METHODS AND COMPOSITIONS FOR GENERATING HUMAN MIDBRAIN DOPAMINERGIC NEURONS FROM NEURAL PROGENITOR CELLS Trailhead Biosystems Inc. (US) 2025-05-28 EP claimed
CN-120051560-A Methods and compositions for generating human midbrain dopaminergic neurons from neural progenitor cells 特雷尔赫德生物系统股份有限公司 2025-05-27 CN claimed
CN-119654404-A Methods and compositions for producing oligodendrocyte progenitor cells 特雷尔赫德生物系统股份有限公司 2025-03-18 CN claimed
CN-117126801-B Preparation method, product and application of high-regeneration subcultured fibrochondrocytes 呈诺再生医学科技(北京)有限公司 2025-01-21 CN claimed
US-12115140-B2 Method of treating adenoid cystic carcinoma THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-10-15 US claimed
WO-2024211636-A1 COMPOSITIONS AND METHODS RELATED TO INHIBITION OF ADENOMAS AND ADENOCARCINOMA THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-10-10 WO claimed
WO-2024063818-A9 METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. (US) 2024-05-23 WO claimed
CN-117887658-A Method for differentiating human pluripotent stem cells into natural killer cells and application thereof 浙江霍德生物工程有限公司 2024-04-16 CN claimed
US-20100144683-A1 METHODS FOR GENERATING MAMMALIAN MODELS OF ATOPIC DISEASES, AND SCREENING FOR THEIR TREATMENT ASSOCIATION POUR LA RECHERCHE A L'IGBMC (ARI) (FR) 2010-06-10 US claimed
US-20090118264-A1 Medicament having neovascularization promoting action RESEARCH FOUNDATION ITSUU LABORATORY (JP) 2009-05-07 US claimed
EP-2046309-A2 USE OF VITAMIN D3 AGONIST IN A MAMMALIAN MODEL FOR ATOPIC DISEASES AND OF VITAMIN D3 ANTAGONISTS FOR THE TREATMENT OF ATOPIC DISEASES Association pour la recherche à l'IGBMC (ARI) (FR) 2009-04-15 EP claimed
EP-1891944-A1 Use of Vitamin D3 agonist in a mammalian model for atopic diseases and of Vitamin D3 antagonists for the treatment of atopic diseases Association pour la recherche à l'IGBMC (ARI) (FR) 2008-02-27 EP claimed
WO-2008012645-A2 USE OF VITAMIN D3 AGONIST IN A MAMMALIAN MODEL FOR ATOPIC DISEASES AND OF VITAMIN D3 ANTAGONISTS FOR THE TREATMENT OF ATOPIC DISEASES ASSOCIATION POUR LA RECHERCHE A L'IGBMC (ARI) (FR) 2008-01-31 WO claimed
EP-0874626-B1 USE OF INHIBITORS OF RETINOIC ACID ACTIVITY FOR WOUND HEALING CT INTERNAT DERECH S DERMATOLO (FR) 2004-12-29 EP claimed
WO-2004045595-A1 USE OF AN RAR RECEPTOR ANTAGONIST FOR POTENTIATING THE ACTION OF TGFβ GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2004-06-03 WO claimed
EP-0892633-B1 USE OF INHIBITORS OF THE ACTIVITY OF RETINOIC ACID FOR TREATING SENSITIVE SKIN AND/OR ACUTE DAMAGE INDUCED BY UV RADIATION GALDERMA RECH DERMATOLOGIQUE (FR) 2003-03-05 EP claimed
US-6248749-B1 TOPICALLY APPLYING RETINOID ANTAGONIST TO SENSITIVE SKIN TO TREAT ALLERGIES/SUNBURN CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) 2001-06-19 US claimed
US-5973007-A SURGERY, TRAUMA WOUNDS CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) 1999-10-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034081-A1 COMPOSITIONS AND METHODS RELATED TO INHIBITION OF ADENOMAS AND ADENOCARCINOMAS RARB, RARA, ADGRF1 RARB 1/4885RARG 4/4885RARA 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.