Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29197600 | 0.88 | MAPT (0.48) | MAPTALPLHTTNR4A2CREBBP | |
| SCHEMBL4416095 | 0.79 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL22644115 | 0.78 | MEN1 (0.63) | MAPTNR4A2CREBBPMEN1KMT2A | |
| SCHEMBL21366110 | 0.77 | MAPT (0.72) | MAPTALPLHTTNR4A2CREBBP | |
| SCHEMBL17749529 | 0.76 | PDE4B (0.55) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL27792887 | 0.74 | NR4A2 (0.45) | MAPTALPLHTTNR4A2CREBBP | |
| SCHEMBL28502410 | 0.74 | JAK2 (0.44) | NR4A2CYP3A4 | |
| SCHEMBL6428705 | 0.74 | MAPT (0.51) | MAPTHTTMEN1KMT2ATUBB4A | |
| SCHEMBL6386434 | 0.74 | HDAC1 (0.65) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29201423 | 0.73 | MAPT (0.53) | MAPTALPLHTTNR4A2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433176-A | Almazole D alkaloid derivative containing thiourea structure and preparation method and application thereof | 河北工业大学 | 2022-12-06 | — | — | CN | disclosed |