Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30909329 | 0.84 | BRD4 (0.52) | MAPTKDM4EMEN1KMT2AGPR84 | |
| SCHEMBL23421579 | 0.76 | KMT2A (0.52) | KDM4EMEN1KMT2AALDH1A1GAA | |
| SCHEMBL627446 | 0.76 | LMNA (0.44) | MAPTHTTKDM4EMEN1KMT2A | |
| SCHEMBL29197598 | 0.76 | ALDH1A1 (0.53) | MAPTALPLHTTNR4A2CREBBP | |
| SCHEMBL1969272 | 0.75 | ADORA2A (0.64) | MAPTHTTKDM4EMEN1KMT2A | |
| SCHEMBL12898707 | 0.75 | LMNA (0.48) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL29197609 | 0.74 | MAPT (0.47) | MAPTALPLHTTNR4A2CREBBP | |
| SCHEMBL4068646 | 0.74 | L3MBTL1 (0.47) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL30100928 | 0.73 | MAPT (0.52) | MAPTALPLHTTNR4A2CREBBP | |
| SCHEMBL29197586 | 0.73 | IKBKB (0.49) | MAPTALPLHTTNR4A2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433176-B | Almazole D alkaloid derivative containing thiourea structure and preparation method and application thereof | 河北工业大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-115433176-A | Almazole D alkaloid derivative containing thiourea structure and preparation method and application thereof | 河北工业大学 | 2022-12-06 | — | — | CN | disclosed |