Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18110503 | 0.90 | BRD4 (0.41) | BRD4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL30100978 | 0.81 | USP2 (0.43) | BRD4SMN1; SMN2MAPTALDH1A1BRDT | |
| SCHEMBL4730362 | 0.77 | USP30 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1USP30 | |
| SCHEMBL4730357 | 0.77 | USP30 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1USP30 | |
| SCHEMBL22653556 | 0.76 | KDM4E (0.42) | BRD4SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL8664503 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL18110505 | 0.75 | SMN1; SMN2 (0.39) | BRD4SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL27223458 | 0.72 | USP30 (0.40) | RAB9AALDH1A1USP30POLBTSHR | |
| SCHEMBL30100998 | 0.72 | CNR2 (0.53) | POLBCYP3A4 | |
| SCHEMBL3790233 | 0.72 | USP30 (0.44) | ALDH1A1USP30MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433205-A | Polycyclic derivative receptor agonist, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |