Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27892863 | 0.84 | DRD2 (0.48) | DRD2DRD3HTR1A | |
| SCHEMBL31116731 | 0.73 | DRD2 (0.49) | DRD2DRD3HTR1ASLC6A3 | |
| SCHEMBL30101005 | 0.71 | KIF11 (0.31) | — | |
| SCHEMBL30373416 | 0.70 | DRD2 (0.35) | DRD2DRD3HTR1A | |
| SCHEMBL30374018 | 0.70 | TSHR (0.47) | DRD2DRD3HTR1A | |
| SCHEMBL30373783 | 0.68 | DRD2 (0.36) | DRD2DRD3HTR1A | |
| SCHEMBL31116696 | 0.68 | — | — | |
| SCHEMBL31116756 | 0.68 | — | — | |
| SCHEMBL31116767 | 0.68 | DRD2 (0.43) | DRD2DRD3HTR1A | |
| SCHEMBL31116699 | 0.67 | DRD2 (0.49) | DRD2DRD3HTR1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433205-A | Polycyclic derivative receptor agonist, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |