Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 4/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292922 | 0.84 | HIF1A (0.41) | HIF1APDGFRBKDRALDH1A1NPC1 | |
| SCHEMBL29131944 | 0.80 | CA1 (0.39) | HIF1APDGFRBKDRNPC1CA12 | |
| SCHEMBL7162437 | 0.78 | LPL (0.38) | HIF1ALPLLIPGALDH1A1NPC1 | |
| SCHEMBL29424563 | 0.78 | LPL (0.38) | HIF1ALPLLIPGALDH1A1NPC1 | |
| SCHEMBL16967649 | 0.77 | LPL (0.43) | LPLLIPGALDH1A1MAPTRAB9A | |
| SCHEMBL6120636 | 0.75 | LPL (0.41) | HIF1APDGFRBKDRLPLLIPG | |
| SCHEMBL16558543 | 0.75 | LPL (0.34) | HIF1ALPLLIPGCA1CA2 | |
| SCHEMBL771975 | 0.75 | TDP1 (0.48) | LPLLIPGALDH1A1NPC1MAPT | |
| SCHEMBL15476117 | 0.75 | TRPA1 (0.43) | HIF1ALPLLIPGALDH1A1GAA | |
| SCHEMBL37395635 | 0.75 | LPL (0.41) | HIF1APDGFRBKDRLPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253326-A1 | NLRP3 INFLAMMASOME INHIBITOR AND APPLICATION THEREOF | 药捷安康(南京)科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |