Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 12/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849842 | 1.00 | ILK (0.64) | ILKRAB9ANPC1SMN1; SMN2DRD2 | |
| SCHEMBL30101763 | 0.89 | RAB9A (0.62) | ILKRAB9ANPC1SMN1; SMN2DRD2 | |
| SCHEMBL28849853 | 0.89 | RAB9A (0.62) | ILKRAB9ANPC1SMN1; SMN2DRD2 | |
| SCHEMBL28636881 | 0.84 | RAB9A (0.56) | ILKRAB9ANPC1SMN1; SMN2DRD2 | |
| SCHEMBL30101637 | 0.84 | RAB9A (0.55) | ILKRAB9ANPC1SMN1; SMN2DRD2 | |
| SCHEMBL17747833 | 0.84 | RAB9A (0.61) | ILKRAB9ANPC1SMN1; SMN2DRD2 | |
| SCHEMBL28849859 | 0.84 | RAB9A (0.55) | ILKRAB9ANPC1SMN1; SMN2DRD2 | |
| SCHEMBL686551 | 0.79 | ILK (0.76) | ILKLMNA | |
| SCHEMBL28849843 | 0.78 | PIK3CA (0.57) | ILKRAB9ANPC1SMN1; SMN2DRD2 | |
| SCHEMBL30101645 | 0.78 | PIK3CA (0.57) | ILKRAB9ANPC1SMN1; SMN2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109011-B | Benzothiazole compound, preparation method and application | 河北师范大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-115109011-A | Benzothiazole compound, preparation method and application | 河北师范大学 | 2022-09-27 | — | — | CN | disclosed |