Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 4/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30101838 | 0.90 | PIM1 (0.36) | SYKKCNH2PIM1 | |
| SCHEMBL30101893 | 0.90 | PIM1 (0.36) | SYKKCNH2PIM1 | |
| SCHEMBL30101867 | 0.85 | PIM1 (0.37) | KCNH2PIM1 | |
| SCHEMBL30101911 | 0.81 | JAK2 (0.40) | SYKPIM1PIK3CA | |
| SCHEMBL30101942 | 0.80 | CDK5 (0.41) | PIM1HSP90AA1 | |
| SCHEMBL23950604 | 0.77 | CLK1 (0.36) | SYKKCNH2PIM1PIK3CAHSP90AA1 | |
| SCHEMBL23925639 | 0.77 | CLK1 (0.36) | SYKKCNH2PIM1PIK3CAHSP90AA1 | |
| SCHEMBL31472842 | 0.77 | MAPK13 (0.42) | KCNH2PIM1 | |
| SCHEMBL30101836 | 0.77 | TRPV3 (0.39) | SYKKCNH2PTGS1PTGS2 | |
| SCHEMBL30101987 | 0.77 | PIM1 (0.37) | SYKKCNH2PIM1HSP90AA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | claimed |
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |