Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30101920 | 0.90 | PIM1 (0.38) | PIM1PIM2PTGS1PTGS2KCNH2 | |
| SCHEMBL30101885 | 0.83 | TRPV3 (0.40) | PTGS1PTGS2PTGESKCNH2SYK | |
| SCHEMBL30101836 | 0.83 | TRPV3 (0.39) | PTGS1PTGS2PTGESKCNH2SYK | |
| SCHEMBL23390340 | 0.79 | PIM1 (0.40) | PIM1PTGS1PTGS2 | |
| SCHEMBL29611095 | 0.79 | PIM1 (0.40) | PIM1PTGS1PTGS2 | |
| SCHEMBL23390465 | 0.78 | SYK (0.40) | PIM1PTGS1PTGS2HSP90AA1KCNH2 | |
| SCHEMBL30101897 | 0.77 | SYK (0.35) | PIM1PTGS1PTGS2HSP90AA1KCNH2 | |
| SCHEMBL30101960 | 0.74 | PIM1 (0.37) | PIM1PIM2PTGS1PTGS2KCNH2 | |
| SCHEMBL30101994 | 0.74 | PTGS2 (0.40) | PIM1PIM2PTGS1PTGS2KCNH2 | |
| SCHEMBL23416810 | 0.74 | CYP2E1 (0.41) | PIM1PTGS1PTGS2HSP90AA1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | claimed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |