Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 3/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31472805 | 0.92 | PIM1 (0.39) | PIM1NPY5RDGAT1KCNH2PTGS1 | |
| SCHEMBL30101858 | 0.91 | AHR (0.38) | AHRPIM1NPY5RDGAT1KCNH2 | |
| SCHEMBL30101887 | 0.91 | PIM1 (0.39) | AHRPIM1NPY5RDGAT1KCNH2 | |
| SCHEMBL30101836 | 0.90 | TRPV3 (0.39) | AHRKCNH2PTGS1PTGS2 | |
| SCHEMBL31472804 | 0.90 | PIM1 (0.37) | AHRPIM1NPY5RDGAT1KCNH2 | |
| SCHEMBL30101864 | 0.89 | AHR (0.52) | AHRNPY5RKCNH2CYP11B1CYP11B2 | |
| SCHEMBL30101960 | 0.84 | PIM1 (0.37) | AHRPIM1NPY5RDGAT1KCNH2 | |
| SCHEMBL30101831 | 0.84 | NPBWR1 (0.40) | PDE2ATNKSTNKS2PARP2PARP1 | |
| SCHEMBL31472815 | 0.82 | NPBWR1 (0.40) | PDE2ATNKSTNKS2PARP2 | |
| SCHEMBL30101920 | 0.82 | PIM1 (0.38) | PIM1NPY5RDGAT1KCNH2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | claimed |
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |