Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24811060 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KMT2AGAARAB9AAPAF1 | |
| SCHEMBL24812565 | 0.83 | USP2 (0.61) | ALDH1A1GAARAB9AHSD17B10HPGD | |
| SCHEMBL24811042 | 0.81 | USP2 (0.49) | ALDH1A1KMT2AGAARAB9AAPAF1 | |
| SCHEMBL20124834 | 0.81 | KMT2A (0.68) | ALDH1A1KMT2AGAARAB9AAPAF1 | |
| SCHEMBL24813932 | 0.81 | KMT2A (0.46) | ALDH1A1KMT2AGAARAB9AAPAF1 | |
| SCHEMBL24813897 | 0.80 | KMT2A (0.62) | ALDH1A1KMT2AGAARAB9AAPAF1 | |
| SCHEMBL31395586 | 0.80 | KMT2A (0.70) | ALDH1A1KMT2AGAARAB9AAPAF1 | |
| SCHEMBL24811059 | 0.80 | KMT2A (0.70) | ALDH1A1KMT2AGAARAB9AAPAF1 | |
| SCHEMBL9393236 | 0.78 | KMT2A (0.57) | ALDH1A1KMT2AGAARAB9AAPAF1 | |
| SCHEMBL24811062 | 0.76 | USP2 (0.77) | ALDH1A1KMT2AGAARAB9AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |