Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191244 | 0.86 | HPGD (0.46) | SMN1; SMN2HPGDLMNANPC1RAB9A | |
| SCHEMBL30275232 | 0.86 | HPGD (0.46) | SMN1; SMN2HPGDLMNANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8478843 | 0.85 | HPGD (0.45) | SMN1; SMN2HPGDLMNANPC1RAB9A | |
| Iodide SCHEMBL8481287 | 0.85 | HPGD (0.45) | SMN1; SMN2HPGDLMNANPC1RAB9A | |
| SCHEMBL8478862 | 0.76 | CYP2C19 (0.44) | SMN1; SMN2HPGDLMNANPC1RAB9A | |
| SCHEMBL10444586 | 0.73 | PDE3B (0.46) | SMN1; SMN2HPGDLMNANPC1RAB9A | |
| SCHEMBL4505370 | 0.73 | HPGD (0.45) | SMN1; SMN2HPGDLMNAPOLBACHE | |
| SCHEMBL28842567 | 0.73 | DAO (0.43) | SMN1; SMN2HPGDLMNANPC1RAB9A | |
| SCHEMBL28242818 | 0.72 | HPGD (0.53) | SMN1; SMN2HPGDLMNANPC1RAB9A | |
| SCHEMBL8482902 | 0.70 | KDM4E (0.50) | SMN1; SMN2HPGDLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282783-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. | 2025-09-11 | — | — | US | disclosed |
| US-20240393343-A1 | METHODS AND MATERIALS FOR LARGE-SCALE ASSESSMENT OF LIGAND BINDING SELECTIVITY OF G-QUADRUPLEX RECOGNITION USING CUSTOM G4 MICROARRAYS | PURDUE RESEARCH FOUNDATION (US) | 2024-11-28 | — | — | US | disclosed |
| US-20240358842-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. | 2024-10-31 | — | — | US | disclosed |
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250282783-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | USP28, USP25, USP24 | SMN1; SMN2 2692/4885HPGD 3874/4885LMNA 3720/4885 |
| US-20240358842-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | USP7, UBQLN1, UBQLN2 | SMN1; SMN2 944/4885HPGD 4428/4885LMNA 3276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.