SCHEMBL30102407

SCHEMBL30102407

CNC(=O)C(=N)C(C)=CCOc1ccn(-c2ccc(Cl)cc2F)n1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 3/20 0.32
S1PR3 Q99500 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
KCNH2 Q12809 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
TPH1 P17752 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18823502 0.87 NUDT1 (0.32) NUDT1
SCHEMBL29367593 0.87 NUDT1 (0.33) NUDT1
SCHEMBL16319142 0.87 NUDT1 (0.33) NUDT1
SCHEMBL16319139 0.87 NUDT1 (0.33) NUDT1
SCHEMBL16319140 0.87 NUDT1 (0.33) NUDT1
Methyl Alcohol SCHEMBL20520037 0.83 SIGMAR1 (0.40) CYP1A2CYP3A4KCNH2SIGMAR1
SCHEMBL28660879 0.81 NUDT1 (0.31) NUDT1CYP1A2CYP2C9CYP2C19
SCHEMBL20996047 0.80 FFAR4 (0.30)
SCHEMBL18795818 0.80 FFAR4 (0.30)
SCHEMBL30305379 0.79 HTR2A (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115551352-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2022-12-30 CN claimed
CN-115551352-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2022-12-30 CN disclosed