Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.54 |
| ▸ | GHSR | Q92847 | 6/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905087 | 1.00 | PDK1 (0.54) | PDK1PDK2PDK3PDK4GHSR | |
| SCHEMBL3902299 | 0.96 | PDK1 (0.51) | PDK1PDK2PDK3PDK4GHSR | |
| SCHEMBL3903665 | 0.94 | GHSR (0.49) | PDK1PDK2PDK3PDK4GHSR | |
| SCHEMBL3903564 | 0.92 | NPC1 (0.48) | PDK1PDK2PDK3PDK4GHSR | |
| SCHEMBL17321358 | 0.91 | HRH3 (0.53) | PDK1PDK2PDK3PDK4GHSR | |
| SCHEMBL3905150 | 0.88 | GHSR (0.45) | PDK1PDK2PDK3PDK4GHSR | |
| SCHEMBL13957119 | 0.86 | DHODH (0.45) | PDK1PDK2PDK3PDK4GHSR | |
| SCHEMBL3907882 | 0.85 | TACR1 (0.48) | GHSRSRD5A1DHODHGPR119MAOA | |
| SCHEMBL3902842 | 0.84 | PTPN1 (0.47) | PDK1PDK2PDK3PDK4GHSR | |
| SCHEMBL3912242 | 0.84 | POLB (0.43) | PDK1PDK2PDK3PDK4GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384506-B | Indoline-1-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2023-01-24 | — | — | CN | disclosed |