Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 15/20 | 1.00 |
| ▸ | MAOA | P21397 | 2/20 | 1.00 |
| ▸ | ACHE | P22303 | 2/20 | 0.79 |
| ▸ | BCHE | P06276 | 1/20 | 0.79 |
| ▸ | HASPIN | Q8TF76 | 4/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2216160 | 1.00 | DYRK1A (1.00) | DYRK1AMAOAACHEBCHEHASPIN | |
| SCHEMBL20159056 | 0.88 | ACHE (1.00) | DYRK1AMAOAACHEBCHEHASPIN | |
| SCHEMBL20340616 | 0.86 | DYRK1A (0.88) | DYRK1AMAOAACHEHASPINHTR2A | |
| SCHEMBL17517503 | 0.83 | DYRK1A (0.88) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL13875060 | 0.83 | HASPIN (0.88) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL13874987 | 0.83 | DYRK1A (0.82) | DYRK1AMAOAACHEHASPINHTR2A | |
| SCHEMBL17502361 | 0.82 | HASPIN (0.86) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL17517505 | 0.82 | HASPIN (0.86) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL17502363 | 0.82 | HASPIN (0.86) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL3857445 | 0.82 | HASPIN (0.86) | DYRK1AHASPINHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933598-B | 6-Substituted harmine derivative, and preparation method and application thereof | 乐山职业技术学院 | 2024-07-12 | — | — | CN | disclosed |