Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3617002 | 0.84 | TRPV1 (0.63) | TRPV1MAPK1 | |
| SCHEMBL11949096 | 0.76 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL31511744 | 0.74 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL2360066 | 0.74 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL19976999 | 0.74 | TRPV1 (0.51) | TRPV1NPC1RAB9A | |
| SCHEMBL30006635 | 0.73 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL19976966 | 0.72 | TRPV1 (0.46) | TRPV1NPC1RAB9A | |
| SCHEMBL31320721 | 0.71 | TRPV1 (0.55) | TRPV1NPC1RAB9A | |
| SCHEMBL19977017 | 0.71 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL29334882 | 0.70 | TRPV1 (0.50) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12403139-B2 | Methods and compositions for prevention and treatment of cardiac hypertrophy | UNIVERSITY OF HAWAII (US) | 2025-09-02 | — | — | US | claimed |
| US-20240189303-A1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY | UNIVERSITY OF HAWAII | 2024-06-13 | — | — | US | claimed |
| EP-3393462-B1 | COMPOSITIONS AND METHODS FOR TREATMENT, AMELIORATION, AND PREVENTION OF ANESTHESIA-INDUCED HYPOTHERMIA | UNIV ARIZONA (US) | 2023-02-01 | — | — | EP | claimed |
| US-12186314-B2 | Compositions and methods for treatment, amelioration, and prevention of anesthesia-induced hypothermia | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2025-01-07 | — | — | US | disclosed |
| EP-3348267-B1 | TRPV1 INHIBITOR FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY | UNIV HAWAII (US) | 2024-01-10 | — | — | EP | disclosed |
| EP-3393462-B1 | COMPOSITIONS AND METHODS FOR TREATMENT, AMELIORATION, AND PREVENTION OF ANESTHESIA-INDUCED HYPOTHERMIA | UNIV ARIZONA (US) | 2023-02-01 | — | — | EP | disclosed |