Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977017 | 0.88 | TRPV1 (0.52) | TRPV1KMT2A | |
| SCHEMBL19976999 | 0.85 | TRPV1 (0.51) | TRPV1NPC1RAB9A | |
| SCHEMBL16993926 | 0.84 | MMP2 (0.49) | TRPV1 | |
| SCHEMBL19976994 | 0.80 | PGR (0.57) | NPC1RAB9AKMT2A | |
| SCHEMBL19976963 | 0.78 | TRPV1 (0.56) | TRPV1NPC1RAB9A | |
| SCHEMBL19976940 | 0.78 | TRPV1 (0.55) | TRPV1KMT2A | |
| SCHEMBL19976941 | 0.77 | PGR (0.40) | NPC1RAB9AKMT2A | |
| SCHEMBL19976939 | 0.77 | ALDH1A1 (0.56) | KMT2A | |
| SCHEMBL31511744 | 0.74 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL2360066 | 0.74 | TRPV1 (0.55) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |