Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554715 | 1.00 | RAB9A (0.45) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL4592575 | 0.83 | GFER (0.46) | RAB9ANPC1SMN1; SMN2CYP1A2MAP4K4 | |
| SCHEMBL31434781 | 0.82 | GRM5 (0.38) | SRC | |
| SCHEMBL9425353 | 0.82 | GRM5 (0.38) | SRC | |
| SCHEMBL4591869 | 0.80 | CNR2 (0.48) | RAB9ANPC1SMN1; SMN2MAP4K4MAPT | |
| SCHEMBL25304675 | 0.79 | RAB9A (0.45) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL5114909 | 0.79 | PIK3CA (0.46) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL10271458 | 0.79 | RAB9A (0.45) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL10133262 | 0.79 | TAAR1 (0.50) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL30083604 | 0.79 | TAAR1 (0.50) | RAB9ANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |