Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 13/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103034 | 0.82 | NPC1 (0.56) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30103016 | 0.81 | CYP1A2 (0.52) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28029638 | 0.80 | CLK4 (0.72) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2666349 | 0.79 | CLK4 (0.70) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31230014 | 0.79 | CLK4 (0.70) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25269044 | 0.79 | CLK4 (0.70) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12302829 | 0.78 | CLK4 (1.00) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25220297 | 0.78 | CLK4 (0.68) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31230006 | 0.78 | CLK4 (0.68) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30447335 | 0.78 | CLK4 (0.68) | CLK4DYRK1ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |