Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.52 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.52 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.52 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.52 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.52 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.52 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103046 | 0.81 | CLK4 (0.62) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL30103034 | 0.80 | NPC1 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL30103118 | 0.76 | PHF8 (0.40) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL30103109 | 0.76 | PDGFRB (0.48) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL24784603 | 0.74 | KDM1A (0.40) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL30103072 | 0.74 | KDM1A (0.40) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL25365883 | 0.69 | ABL1 (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL22044476 | 0.68 | KDM4E (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL24784608 | 0.66 | KDM1A (0.40) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL21847247 | 0.66 | NOS2 (0.62) | CYP2C9MAPTALDH1A1TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |