Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | FOS | P01100 | 1/20 | 0.31 |
| ▸ | JUN | P05412 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24784628 | 1.00 | ALKBH1 (0.34) | ALKBH1ROCK2P2RX7EPHX2PPARG | |
| SCHEMBL24785463 | 0.94 | ALKBH1 (0.36) | ALKBH1ROCK2P2RX7EPHX2PPARG | |
| SCHEMBL30103069 | 0.94 | ALKBH1 (0.36) | ALKBH1ROCK2P2RX7EPHX2PPARG | |
| SCHEMBL30017666 | 0.90 | ALKBH1 (0.36) | ALKBH1ROCK2P2RX7EPHX2PPARG | |
| SCHEMBL24784629 | 0.90 | ALKBH1 (0.36) | ALKBH1ROCK2P2RX7EPHX2PPARG | |
| SCHEMBL24784614 | 0.89 | P2RX7 (0.39) | ALKBH1ROCK2P2RX7EPHX2PPARG | |
| SCHEMBL30103053 | 0.89 | P2RX7 (0.39) | ALKBH1ROCK2P2RX7EPHX2PPARG | |
| SCHEMBL24784634 | 0.87 | GRIN1 (0.34) | ALKBH1ROCK2P2RX7EPHX2PPARG | |
| SCHEMBL30017932 | 0.87 | GRIN1 (0.34) | ALKBH1ROCK2P2RX7EPHX2PPARG | |
| SCHEMBL24785460 | 0.85 | ALKBH1 (0.41) | ALKBH1ROCK2P2RX7EPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |