Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 7/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PKLR | P30613 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30018129 | 1.00 | BRD4 (0.41) | BRD4CACNA1HMCHR1ALDH1A1MAPK1 | |
| SCHEMBL24785079 | 0.94 | CACNA1H (0.40) | BRD4CACNA1HALKBH1 | |
| SCHEMBL30018338 | 0.94 | CACNA1H (0.40) | BRD4CACNA1HALKBH1 | |
| SCHEMBL30103017 | 0.92 | ALKBH1 (0.40) | BRD4CACNA1HMCHR1ALDH1A1MAPK1 | |
| SCHEMBL24785368 | 0.92 | ALKBH1 (0.40) | BRD4CACNA1HMCHR1ALDH1A1MAPK1 | |
| SCHEMBL30103083 | 0.90 | BRD4 (0.41) | BRD4CACNA1HMCHR1GRM2PKM | |
| SCHEMBL24784564 | 0.86 | NPBWR1 (0.41) | BRD4MCHR1L3MBTL1 | |
| SCHEMBL30103029 | 0.86 | NPBWR1 (0.41) | BRD4MCHR1L3MBTL1 | |
| SCHEMBL24785076 | 0.86 | ALKBH1 (0.41) | CACNA1HALKBH1 | |
| SCHEMBL30103094 | 0.86 | ALKBH1 (0.41) | CACNA1HALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257960-A1 | BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES | 武汉人福创新药物研发中心有限公司 | 2022-12-15 | — | — | WO | disclosed |