Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23931384 | 1.00 | PRKD1 (0.49) | PRKD1RAB9ANPC1SMN1; SMN2USP2 | |
| SCHEMBL23958135 | 0.91 | PRKD1 (0.49) | PRKD1RAB9ANPC1SMN1; SMN2USP2 | |
| SCHEMBL24111024 | 0.80 | USP2 (0.43) | RAB9ANPC1USP2MAPTALDH1A1 | |
| SCHEMBL24110866 | 0.78 | USP2 (0.43) | RAB9ANPC1USP2MAPTALDH1A1 | |
| SCHEMBL23958140 | 0.78 | RAB9A (0.43) | RAB9ANPC1USP2MAPTALDH1A1 | |
| SCHEMBL30103292 | 0.75 | TGFBR1 (0.51) | RAB9AUSP2MAPTALDH1A1KDM4E | |
| SCHEMBL23931430 | 0.75 | TGFBR1 (0.51) | RAB9AUSP2MAPTALDH1A1KDM4E | |
| SCHEMBL24110951 | 0.74 | USP2 (0.44) | RAB9ANPC1USP2MAPTALDH1A1 | |
| SCHEMBL24090010 | 0.74 | USP2 (0.52) | RAB9ANPC1USP2MAPTALDH1A1 | |
| SCHEMBL24090012 | 0.74 | TOP2A (0.60) | RAB9ANPC1USP2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427399-A | 2-heteroarylaminoquinazolinone derivatives | 住友制药株式会社 | 2022-12-02 | — | — | CN | disclosed |