Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902556 | 0.81 | HK1 (0.56) | CA2CA1NPC1RAB9A | |
| SCHEMBL25867027 | 0.81 | CA2 (0.47) | OGACA2CA9CA1LGALS8 | |
| SCHEMBL4169921 | 0.80 | CA2 (0.52) | CA2CA9CA1LGALS8POLB | |
| SCHEMBL4169929 | 0.80 | CA2 (0.52) | CA2CA9CA1LGALS8POLB | |
| SCHEMBL24256553 | 0.77 | LGALS8 (0.59) | CA2CA9CA1LGALS8POLB | |
| SCHEMBL14478851 | 0.77 | CA2 (0.52) | CA2CA9CA1LGALS8 | |
| SCHEMBL26879437 | 0.77 | LGALS8 (0.59) | CA2CA9CA1LGALS8POLB | |
| SCHEMBL26877207 | 0.77 | CA2 (0.44) | OGACA2CA9CA1LGALS8 | |
| SCHEMBL23705211 | 0.76 | CA2 (0.43) | OGACA2CA9CA1LGALS8 | |
| SCHEMBL9233052 | 0.76 | OGA (0.49) | OGACA2CA9CA1LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |