Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL331981 | 1.00 | SLC22A1 (0.52) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| Tetrabuthylammonium SCHEMBL2398988 | 0.98 | SLC22A1 (0.50) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| Tetrabuthylammonium SCHEMBL2398990 | 0.98 | SLC22A1 (0.50) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| L-Lactic Acid SCHEMBL9630451 | 0.96 | SLC22A1 (0.52) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| L-Lactic Acid SCHEMBL29256387 | 0.94 | SLC22A1 (0.54) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| Tetrabuthylammonium SCHEMBL1691312 | 0.89 | SLC22A1 (0.55) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| Tetrabuthylammonium SCHEMBL107578 | 0.87 | SLC22A1 (0.52) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| Tetrabuthylammonium SCHEMBL5874496 | 0.87 | SLC22A1 (0.52) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| Tetrapropylammonium SCHEMBL5574321 | 0.86 | SLC22A1 (0.48) | SLC22A1CA1CA2CYP3A4TSHR | |
| Tetrabuthylammonium SCHEMBL31025702 | 0.85 | SLC22A1 (0.50) | SLC22A1CA1SLC22A2CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011453-A1 | USE OF LACTATE IN PREPARATION OF DRUG FOR PROMOTING GROWTH AND REPAIR OF BONE/CARTILAGE TISSUE | 长春圣博玛生物材料有限公司 | 2025-01-16 | — | — | WO | claimed |
| CN-119302937-A | Application of lactate in preparation of medicine for promoting bone/cartilage tissue growth and repair | 长春圣博玛生物材料有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-119302937-B | Application of lactate in preparation of medicine for promoting bone/cartilage tissue growth and repair | 长春圣博玛生物材料有限公司 | 2026-01-09 | — | — | CN | disclosed |
| US-20250108019-A1 | USE OF LACTIC ACID IN PRODUCT FOR REGULATING AND PROMOTING TISSUE GROWTH | CHANGCHUN SINOBIOMATERIALS CO., LTD. (CN) | 2025-04-03 | — | — | US | disclosed |
| WO-2025011453-A1 | USE OF LACTATE IN PREPARATION OF DRUG FOR PROMOTING GROWTH AND REPAIR OF BONE/CARTILAGE TISSUE | 长春圣博玛生物材料有限公司 | 2025-01-16 | — | — | WO | disclosed |
| WO-2025011453-A1 | USE OF LACTATE IN PREPARATION OF DRUG FOR PROMOTING GROWTH AND REPAIR OF BONE/CARTILAGE TISSUE | 长春圣博玛生物材料有限公司 | 2025-01-16 | — | — | WO | disclosed |
| CN-119302937-A | Application of lactate in preparation of medicine for promoting bone/cartilage tissue growth and repair | 长春圣博玛生物材料有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119302937-A | Application of lactate in preparation of medicine for promoting bone/cartilage tissue growth and repair | 长春圣博玛生物材料有限公司 | 2025-01-14 | — | — | CN | disclosed |
| EP-4464315-A1 | USE OF LACTIC ACID IN PRODUCT FOR REGULATING AND PROMOTING TISSUE GROWTH | Changchun Sinobiomaterials Co., Ltd. (CN) | 2024-11-20 | — | — | EP | disclosed |
| CN-115350110-A | Use of vitamin C lactate and its analogues in preparation of skin tissue products and related products | 长春圣博玛生物材料有限公司 | 2022-11-18 | — | — | CN | disclosed |