Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL9094501 | 0.96 | SLC22A1 (0.52) | SLC22A1SLC22A2CA2ALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL5874528 | 0.94 | SLC22A1 (0.46) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| Tetrabuthylammonium SCHEMBL30104046 | 0.87 | SLC22A1 (0.52) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| Tetrabuthylammonium SCHEMBL331981 | 0.87 | SLC22A1 (0.52) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| Tetrapropylammonium SCHEMBL5874097 | 0.86 | SLC22A1 (0.48) | SLC22A1CA1CA2CYP3A4TSHR | |
| Tetrabuthylammonium SCHEMBL109269 | 0.86 | SLC22A1 (0.63) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL9315609 | 0.86 | SLC22A1 (0.63) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Cadaverine Tartrate SCHEMBL15561037 | 0.85 | SLC22A1 (0.45) | SLC22A1SLC22A2CA2ALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL2398990 | 0.85 | SLC22A1 (0.50) | SLC22A1CA1SLC22A2CA2ALDH1A1 | |
| Tetrabuthylammonium SCHEMBL2398988 | 0.85 | SLC22A1 (0.50) | SLC22A1CA1SLC22A2CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160141725-A1 | Electrolytes and Metal Hydride Batteries | BASF CORPORATION | 2016-05-19 | — | — | US | claimed |
| EP-0398615-B1 | PROCESS FOR SOLUBILIZING POLYANIONIC BACTERIAL POLYSACCHARIDES IN APROTIC SOLVENTS | MERCK & CO. INC. (US) | 1993-07-14 | — | — | EP | claimed |
| EP-0398615-A2 | Process for solubilizing polyanionic bacterial polysaccharides in aprotic solvents | MERCK & CO. INC. (US) | 1990-11-22 | — | — | EP | claimed |
| US-4963534-A | Process for solubilizing polyanoinic bacterial polysaccharides in aprotic solvents | MERCK & CO., INC. (US) | 1990-10-16 | — | — | US | claimed |
| CN-107710462-B | Electrochemical hydrogen storage electrode and battery | 巴斯夫公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-107004912-B | Electrolyte and metal hydride battery | 巴斯夫公司 | 2021-07-30 | — | — | CN | disclosed |
| EP-3292578-B1 | ELECTROCHEMICAL HYDROGEN STORAGE ELECTRODES AND CELLS | BASF CORP (US) | 2021-02-24 | — | — | EP | disclosed |
| US-10243240-B2 | Electrolytes and metal hydride batteries | BASF CORPORATION (US) | 2019-03-26 | — | — | US | disclosed |
| EP-3292578-A1 | ELECTROCHEMICAL HYDROGEN STORAGE ELECTRODES AND CELLS | BASF Corporation (US) | 2018-03-14 | — | — | EP | disclosed |
| EP-3218955-A1 | ELECTROLYTES AND METAL HYDRIDE BATTERIES | BASF Corporation (US) | 2017-09-20 | — | — | EP | disclosed |
| CN-107004912-A | Electrolyte and metal hydride battery | 巴斯夫公司 | 2017-08-01 | — | — | CN | disclosed |
| US-20160329560-A1 | Electrochemical Hydrogen Storage Electrodes and Cells | BASF CORPORATION (US) | 2016-11-10 | — | — | US | disclosed |
| US-20160141725-A1 | Electrolytes and Metal Hydride Batteries | BASF CORPORATION | 2016-05-19 | — | — | US | disclosed |
| US-20160141724-A1 | Electrolytes and Metal Hydride Batteries | BASF CORPORATION | 2016-05-19 | — | — | US | disclosed |
| US-20160141727-A1 | Electrolytes and Metal Hydride Batteries | BASF CORPORATION | 2016-05-19 | — | — | US | disclosed |
| US-20160141726-A1 | Electrolytes and Metal Hydride Batteries | BASF CORPORATION | 2016-05-19 | — | — | US | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-5933693-A | Electroconductive elastic member and electrophotographic apparatus using same | BRIDGESTONE CORPORATION (JP) | 1999-08-03 | — | — | US | disclosed |
| US-5576459-A | Quaternary nitrogen or phosphorus chirates | SACHEM, INC. (US) | 1996-11-19 | — | — | US | disclosed |