Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.75 |
| ▸ | GABRD | O14764 | 2/20 | 0.75 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.75 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.75 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.75 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.75 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.75 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.75 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.75 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.75 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.75 |
| ▸ | GABRE | P78334 | 2/20 | 0.75 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.75 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.75 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.75 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28916429 | 1.00 | GABRP (0.75) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30104121 | 1.00 | GABRP (0.75) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28047536 | 0.87 | GABRA1 (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29817540 | 0.87 | GABRP (0.84) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28290030 | 0.86 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30104123 | 0.86 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28291469 | 0.84 | GABRP (0.82) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28290033 | 0.83 | GABRP (0.77) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28291468 | 0.82 | GABRP (0.79) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2361114 | 0.81 | GABRP (0.77) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115353546-B | Preparation and application of oligopeptide modified bisindolylethyl-beta-carboline-3-carboxylic acid | 首都医科大学 | 2024-10-08 | — | — | CN | disclosed |
| CN-115353546-A | Preparation and application of oligopeptide-modified bis-indolylethyl-beta-carboline-3-carboxylic acid | 首都医科大学 | 2022-11-18 | — | — | CN | disclosed |