Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PRNP | P04156 | 2/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23572608 | 1.00 | MAPT (0.36) | MAPTMAPK1KDM4ELMNAHPGD | |
| SCHEMBL161727 | 0.87 | ALOX5 (0.39) | MAPTKDM4ELMNAHPGDPDK2 | |
| SCHEMBL1813707 | 0.83 | MEN1 (0.42) | MAPTKDM4EPDK2ALDH1A1MEN1 | |
| SCHEMBL160603 | 0.83 | PDK2 (0.37) | MAPTMAPK1KDM4ELMNAPDK2 | |
| SCHEMBL21582139 | 0.83 | MAPT (0.33) | MAPTMAPK1KDM4ELMNAHPGD | |
| SCHEMBL30104204 | 0.83 | MAPT (0.33) | MAPTMAPK1KDM4ELMNAHPGD | |
| SCHEMBL29664007 | 0.82 | CSNK2A2 (0.34) | PDK2ESR2MEN1KMT2A | |
| SCHEMBL1962962 | 0.82 | CSNK2A2 (0.34) | PDK2ESR2MEN1KMT2A | |
| SCHEMBL1010811 | 0.81 | EGFR (0.38) | PDK2MEN1KMT2AEGFRACLY | |
| SCHEMBL164197 | 0.81 | EGFR (0.38) | PDK2MEN1KMT2AEGFRACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518751-B2 | Photochromic indeno-fused naphthopyran compounds with reduced temperature dependence | TRANSITIONS OPTICAL, LTD. (IE) | 2022-12-06 | — | — | US | disclosed |
| EP-3802508-B1 | PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRAN COMPOUNDS WITH REDUCED TEMPERATURE DEPENDENCE | TRANSITIONS OPTICAL LTD (IE) | 2022-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518751-B2 | Photochromic indeno-fused naphthopyran compounds with reduced temperature dependence | NR2E3, NR0B2, NR2C2 | MAPT 1835/4885MAPK1 2076/4885KDM4E 4170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.