Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27811549 | 0.81 | GABRP (0.38) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL16751215 | 0.80 | AAK1 (0.34) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL8248471 | 0.80 | AAK1 (0.34) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL30104847 | 0.78 | L3MBTL1 (0.43) | — | |
| SCHEMBL19149609 | 0.78 | AAK1 (0.33) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL7351512 | 0.77 | AAK1 (0.34) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL10473406 | 0.77 | AAK1 (0.34) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL31716095 | 0.76 | L3MBTL1 (0.38) | HDAC6AAK1 | |
| SCHEMBL19149608 | 0.76 | HDAC6 (0.36) | HDAC6HDAC1HDAC2MMP13AAK1 | |
| SCHEMBL6418739 | 0.74 | HDAC6 (0.38) | HDAC6HDAC1HDAC2MMP13AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022247839-A1 | PARP7 INHIBITOR | 山东轩竹医药科技有限公司 | 2022-12-01 | — | — | WO | disclosed |