Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 5/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831640 | 1.00 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2HTTCNR1 | |
| SCHEMBL23831797 | 0.87 | CNR1 (0.47) | RAB9ANPC1SMN1; SMN2HTTCNR1 | |
| SCHEMBL23831704 | 0.85 | HTT (0.45) | RAB9ANPC1SMN1; SMN2HTTCNR1 | |
| SCHEMBL23832093 | 0.85 | HTT (0.47) | RAB9ANPC1SMN1; SMN2HTTCNR1 | |
| SCHEMBL23831654 | 0.83 | MAPT (0.46) | RAB9ANPC1SMN1; SMN2HTTCNR1 | |
| SCHEMBL23832026 | 0.83 | SMARCA2 (0.54) | RAB9ANPC1SMN1; SMN2HTTCNR1 | |
| SCHEMBL23831972 | 0.80 | CNR1 (0.43) | RAB9ANPC1SMN1; SMN2HTTCNR1 | |
| SCHEMBL23832027 | 0.80 | CNR1 (0.50) | RAB9ANPC1SMN1; SMN2HTTCNR1 | |
| SCHEMBL30105096 | 0.80 | CNR1 (0.43) | RAB9ANPC1SMN1; SMN2HTTCNR1 | |
| SCHEMBL23831771 | 0.80 | MAPT (0.56) | RAB9ANPC1SMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |