Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831636 | 1.00 | MEN1 (0.48) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL30105066 | 0.91 | TRPV1 (0.55) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL23831692 | 0.91 | TRPV1 (0.55) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL30105076 | 0.88 | CA12 (0.43) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL23831850 | 0.88 | CA12 (0.43) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL30105047 | 0.88 | SMARCA2 (0.57) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL23831595 | 0.88 | SMARCA2 (0.57) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL23831733 | 0.86 | KDR (0.47) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL23831824 | 0.86 | RAB9A (0.42) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL23831944 | 0.86 | MEN1 (0.45) | MEN1KMT2ARAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |