Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 11/20 | 0.42 |
| ▸ | NPC1 | O15118 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831850 | 1.00 | CA12 (0.43) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL30792378 | 0.88 | RAB9A (0.42) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL30105041 | 0.88 | MEN1 (0.48) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL30105143 | 0.88 | RAB9A (0.44) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL23832086 | 0.88 | RAB9A (0.44) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL23831636 | 0.88 | MEN1 (0.48) | RAB9ANPC1SMN1; SMN2POLBHTT | |
| SCHEMBL23831824 | 0.88 | RAB9A (0.42) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL23831628 | 0.88 | SMARCA2 (0.54) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL30105266 | 0.88 | SMARCA2 (0.54) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL23831829 | 0.86 | RAB9A (0.45) | CA12CA1CA2CA9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |