Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 1.00 |
| ▸ | DRD4 | P21917 | 2/20 | 1.00 |
| ▸ | KDM1A | O60341 | 1/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.80 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | ABL1 | P00519 | 1/20 | 0.79 |
| ▸ | ALPL | P05186 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.70 |
| ▸ | BCHE | P06276 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (+)-Higenamine SCHEMBL5898913 | 1.00 | DRD2 (1.00) | DRD2DRD4KDM1ATBXA2RADRB2 | |
| (+)-Higenamine SCHEMBL30464469 | 1.00 | DRD2 (1.00) | DRD2DRD4KDM1ATBXA2RADRB2 | |
| (-)-Higenamine SCHEMBL29365055 | 1.00 | DRD2 (1.00) | DRD2DRD4KDM1ATBXA2RADRB2 | |
| (-)-Higenamine SCHEMBL5898911 | 1.00 | DRD2 (1.00) | DRD2DRD4KDM1ATBXA2RADRB2 | |
| Higenamine SCHEMBL636788 | 1.00 | DRD2 (1.00) | DRD2DRD4KDM1ATBXA2RADRB2 | |
| (-)-Higenamine SCHEMBL5898916 | 0.99 | DRD2 (0.97) | DRD2DRD4KDM1ATBXA2RADRB2 | |
| (-)-Higenamine SCHEMBL29374757 | 0.99 | DRD2 (0.97) | DRD2DRD4KDM1ATBXA2RADRB2 | |
| (+)-Higenamine SCHEMBL5898932 | 0.99 | DRD2 (0.97) | DRD2DRD4KDM1ATBXA2RADRB2 | |
| Higenamine SCHEMBL28478764 | 0.99 | DRD2 (0.97) | DRD2DRD4KDM1ATBXA2RADRB2 | |
| Higenamine SCHEMBL29623874 | 0.99 | DRD2 (0.97) | DRD2DRD4KDM1ATBXA2RADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536584-B | Synthesis method of norlinderane hydrochloride | 珠海润都制药股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-115536584-A | Synthetic method of higenamine hydrochloride | 珠海润都制药股份有限公司 | 2022-12-30 | — | — | CN | disclosed |