Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 5/20 | 0.34 |
| ▸ | JAK3 | P52333 | 5/20 | 0.34 |
| ▸ | JAK1 | P23458 | 3/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30075002 | 1.00 | PRKCA (0.37) | PRKCAPRKCQSCN9ANPC1JAK2 | |
| SCHEMBL30106037 | 1.00 | PRKCA (0.37) | PRKCAPRKCQSCN9ANPC1JAK2 | |
| SCHEMBL30074993 | 0.91 | GAA (0.34) | PRKCAPRKCQALOX5APFEN1 | |
| SCHEMBL29722758 | 0.90 | PRKCA (0.35) | PRKCAPRKCQSCN9ANPC1PARP1 | |
| SCHEMBL21751548 | 0.90 | PRKCA (0.35) | PRKCAPRKCQSCN9ANPC1PARP1 | |
| SCHEMBL30075016 | 0.90 | PRKCA (0.35) | PRKCAPRKCQSCN9ANPC1PARP1 | |
| SCHEMBL30104711 | 0.87 | SCN9A (0.34) | SCN9ANPC1JAK2JAK3JAK1 | |
| SCHEMBL30073537 | 0.87 | SCN9A (0.34) | SCN9ANPC1JAK2JAK3JAK1 | |
| SCHEMBL30104739 | 0.87 | SCN9A (0.34) | SCN9ANPC1JAK2JAK3JAK1 | |
| SCHEMBL21751582 | 0.83 | SCN9A (0.45) | SCN9ANPC1JAK2JAK3JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110298-A1 | HOT MELT EXTRUDED SOLID DISPERSIONS CONTAINING A BCL2 INHIBITOR | Guangzhou Lupeng Pharmaceutical Company Ltd. (CN) | 2023-01-04 | — | — | EP | disclosed |