⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29748502 | 0.94 | — | — | |
| SCHEMBL25355858 | 0.80 | LMNA (0.33) | — | |
| SCHEMBL23166620 | 0.79 | ADAM17 (0.32) | — | |
| SCHEMBL23166621 | 0.79 | ADAM17 (0.32) | — | |
| SCHEMBL23166619 | 0.79 | ADAM17 (0.32) | — | |
| SCHEMBL30106038 | 0.79 | ADAM17 (0.32) | — | |
| SCHEMBL29747132 | 0.76 | ADAM17 (0.34) | — | |
| SCHEMBL29747201 | 0.76 | ADAM17 (0.34) | — | |
| SCHEMBL29747235 | 0.76 | ADAM17 (0.34) | — | |
| SCHEMBL29747206 | 0.75 | SLC12A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110298-A1 | HOT MELT EXTRUDED SOLID DISPERSIONS CONTAINING A BCL2 INHIBITOR | Guangzhou Lupeng Pharmaceutical Company Ltd. (CN) | 2023-01-04 | — | — | EP | disclosed |