Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | UTRN | P46939 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158640 | 0.91 | HSP90AB1 (0.43) | MAPTIKBKBKDM4EHSP90AB1TRPV1 | |
| SCHEMBL30106330 | 0.87 | KDM4E (0.44) | IKBKBKDM4EHSP90AB1TRPV1SMN1; SMN2 | |
| SCHEMBL29158713 | 0.87 | ABCG2 (0.48) | MAPTIKBKBKDM4EHSP90AB1TRPV1 | |
| SCHEMBL27189106 | 0.86 | SMN1; SMN2 (0.54) | IKBKBKDM4EHSP90AB1TRPV1SMN1; SMN2 | |
| SCHEMBL30740883 | 0.85 | IKBKB (0.46) | IKBKBHSP90AB1TRPV1UTRNHDAC3 | |
| SCHEMBL29158717 | 0.85 | IKBKB (0.46) | IKBKBHSP90AB1TRPV1UTRNHDAC3 | |
| SCHEMBL27189063 | 0.85 | RAB9A (0.45) | MAPTIKBKBKDM4ETRPV1SMN1; SMN2 | |
| SCHEMBL27189103 | 0.84 | IKBKB (0.46) | IKBKBHSP90AB1TRPV1UTRNHDAC3 | |
| SCHEMBL30106359 | 0.84 | GSK3B (0.51) | IKBKBHSP90AB1TRPV1SMN1; SMN2UTRN | |
| SCHEMBL27189116 | 0.84 | IKBKB (0.48) | IKBKBHSP90AB1TRPV1UTRNHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255764-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | disclosed |