Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | UTRN | P46939 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158717 | 1.00 | IKBKB (0.46) | IKBKBTRPV1HSP90AA1HSP90AB1HDAC6 | |
| SCHEMBL27189071 | 0.91 | IKBKB (0.46) | IKBKBTRPV1HSP90AA1HSP90AB1HDAC6 | |
| SCHEMBL27189103 | 0.88 | IKBKB (0.46) | IKBKBTRPV1HSP90AA1HSP90AB1HDAC6 | |
| SCHEMBL27189116 | 0.88 | IKBKB (0.48) | IKBKBTRPV1HSP90AA1HSP90AB1HDAC6 | |
| SCHEMBL30106359 | 0.88 | GSK3B (0.51) | IKBKBTRPV1HSP90AA1HSP90AB1HDAC6 | |
| SCHEMBL30106290 | 0.87 | CASP6 (0.45) | IKBKBTRPV1HSP90AA1HSP90AB1HDAC6 | |
| SCHEMBL27189073 | 0.87 | DGAT1 (0.49) | IKBKBTRPV1HDAC6HDAC3HDAC1 | |
| SCHEMBL30106334 | 0.85 | MAPT (0.47) | IKBKBTRPV1HSP90AB1HDAC6HDAC3 | |
| SCHEMBL30106330 | 0.84 | KDM4E (0.44) | IKBKBTRPV1HSP90AA1HSP90AB1HDAC6 | |
| SCHEMBL29158713 | 0.84 | ABCG2 (0.48) | IKBKBTRPV1HSP90AA1HSP90AB1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |