Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 17/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.51 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21494609 | 1.00 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL21494608 | 1.00 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL21494607 | 0.85 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL30106781 | 0.85 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL21494604 | 0.85 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL21494697 | 0.84 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL30106798 | 0.84 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL21494695 | 0.84 | FPR2 (1.00) | FPR2AKR1B1MTHFD1MTHFD2 | |
| SCHEMBL21494600 | 0.83 | FPR2 (1.00) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL21494599 | 0.83 | FPR2 (1.00) | FPR2MTHFD1MTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12357634-B2 | 2,6-diamino-3,4-dihydropyrimidin-4-one derivatives and use thereof in therapy | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2025-07-15 | — | — | US | claimed |
| US-12357634-B2 | 2,6-diamino-3,4-dihydropyrimidin-4-one derivatives and use thereof in therapy | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2025-07-15 | — | — | US | disclosed |
| US-20230110478-A1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2023-04-13 | — | — | US | disclosed |
| US-11504368-B2 | 2,6-diamino-3,4-dihydropyrimidin-4-one derivatives and use thereof in therapy | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2022-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11504368-B2 | 2,6-diamino-3,4-dihydropyrimidin-4-one derivatives and use thereof in therapy | IL2, THPO, IL6 | FPR2 435/4885AKR1B1 1894/4885MTHFD1 2241/4885 |
| US-20230110478-A1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | IL2, THPO, IL6 | FPR2 406/4885AKR1B1 1937/4885MTHFD1 2281/4885 |
| US-12357634-B2 | 2,6-diamino-3,4-dihydropyrimidin-4-one derivatives and use thereof in therapy | IL2, THPO, IL6 | FPR2 406/4885AKR1B1 1937/4885MTHFD1 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.