SCHEMBL30107040

SCHEMBL30107040

CCS(=O)(=O)c1cncc(C=NO)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
GAA P10253 3/20 0.35
CYP1A2 P05177 3/20 0.35
CYP3A4 P08684 3/20 0.35
CYP2C19 P33261 3/20 0.35
CYP2C9 P11712 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP2D6 P10635 1/20 0.35
NAMPT P43490 1/20 0.33
ACHE P22303 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PSIP1 O75475 1/20 0.32
PLK4 O00444 1/20 0.32
AURKA O14965 1/20 0.32
ROCK2 O75116 1/20 0.32
CHEK2 O96017 1/20 0.32
PIM1 P11309 1/20 0.32
CDK2 P24941 1/20 0.32
FLT4 P35916 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30107071 0.80 PSIP1 (0.36) GAACYP1A2CYP3A4CYP2C19CYP2C9
SCHEMBL28790641 0.80 PSIP1 (0.36) GAACYP1A2CYP3A4CYP2C19CYP2C9
SCHEMBL3464427 0.77 PLK4 (0.40) ALDH1A1GAAMEN1KMT2ANAMPT
SCHEMBL28507967 0.74 ALDH1A1 (0.50) ALDH1A1GAACYP1A2CYP3A4CYP2C19
SCHEMBL568488 0.74 PLK4 (0.38) ALDH1A1GAANAMPTPSIP1PLK4
SCHEMBL25586982 0.73 ALDH1A1 (0.37) ALDH1A1GAACYP1A2CYP3A4CYP2C19
SCHEMBL13358892 0.72 KDR (0.36) ALDH1A1NAMPTPLK4AURKAROCK2
SCHEMBL25891814 0.70 PSIP1 (0.40) ALDH1A1GAACYP1A2CYP3A4CYP2C19
SCHEMBL31375063 0.68 POLB (0.42) CYP1A2CYP3A4CYP2C19KDM4EPSIP1
SCHEMBL26614777 0.68 POLB (0.42) CYP1A2CYP3A4CYP2C19KDM4EPSIP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115551857-A Imidazopyrimidinone compounds as pesticides 巴斯夫欧洲公司 2022-12-30 CN disclosed