Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20519121 | 1.00 | PDXK (0.33) | PDXKRECQLCYP2D6CYP2C19 | |
| SCHEMBL1710157 | 0.78 | PDXK (0.39) | PDXKRECQLCYP2D6CYP2C19 | |
| SCHEMBL30228756 | 0.78 | PDXK (0.39) | PDXKRECQLCYP2D6CYP2C19 | |
| SCHEMBL903627 | 0.77 | PDXK (0.42) | PDXKRECQLCYP2D6CYP2C19 | |
| SCHEMBL3705107 | 0.75 | KMT2A (0.40) | PDXKRECQLCYP2C19 | |
| SCHEMBL29882499 | 0.75 | KMT2A (0.40) | PDXKRECQLCYP2C19 | |
| SCHEMBL26547800 | 0.75 | TDP1 (0.40) | PDXKRECQLCYP2D6CYP2C19 | |
| SCHEMBL18031333 | 0.73 | PKM (0.42) | RECQLCYP2C19 | |
| SCHEMBL903616 | 0.72 | PDXK (0.35) | PDXKCYP2D6CYP2C19 | |
| SCHEMBL7043686 | 0.71 | NOTUM (0.33) | PDXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678466-B | Diazanaphthalenes as HPK1 inhibitors | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |