Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30309358 | 0.67 | — | — | |
| SCHEMBL4748046 | 0.64 | DDB1 (0.31) | DDB1CRBNMAPK1 | |
| SCHEMBL30448722 | 0.61 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL31187659 | 0.61 | BTK (0.31) | — | |
| SCHEMBL7868198 | 0.59 | GAA (0.43) | — | |
| SCHEMBL1710058 | 0.58 | HSD17B10 (0.36) | DDB1CRBNMAPK1 | |
| SCHEMBL15129360 | 0.58 | HSD17B10 (0.36) | DDB1CRBNMAPK1 | |
| SCHEMBL34474146 | 0.58 | DGAT1 (0.32) | MAPK1 | |
| SCHEMBL7567670 | 0.58 | BTK (0.37) | MAPK1 | |
| SCHEMBL6900137 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678466-B | Diazanaphthalenes as HPK1 inhibitors | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |