Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19965689 | 0.78 | NR1I2 (0.38) | NR1I2SLC2A1 | |
| SCHEMBL19464626 | 0.76 | NR1I2 (0.37) | NR1I2CA2SLC2A1 | |
| SCHEMBL31060074 | 0.75 | RARB (0.48) | CA2TP53LCKNPC1ALDH1A1 | |
| SCHEMBL21100746 | 0.74 | GPR84 (0.41) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL19231975 | 0.73 | ITGB3 (0.39) | NR1I2SLC2A1 | |
| SCHEMBL22333698 | 0.73 | NR1I2 (0.65) | NR1I2CA2CACNA1FCHRM2ADRA2B | |
| SCHEMBL19464657 | 0.73 | SLC2A1 (0.36) | NR1I2MAPTHTTNPSR1SLC2A1 | |
| SCHEMBL19332936 | 0.73 | NR1I2 (0.65) | NR1I2CA2CACNA1FCHRM2ADRA2B | |
| SCHEMBL19231976 | 0.73 | ITGB3 (0.39) | NR1I2SLC2A1 | |
| SCHEMBL24804929 | 0.73 | NR1I2 (0.34) | NR1I2CA2SLC2A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253035-A1 | ANTIBODY DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-12-08 | — | — | WO | disclosed |