Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108028 | 0.88 | KDM4E (0.43) | PTGS1PTGS2KDM4EALDH1A1HPGD | |
| SCHEMBL30107973 | 0.88 | KDM4E (0.46) | PTGS1PTGS2KDM4EALDH1A1HPGD | |
| SCHEMBL30107980 | 0.84 | ROCK1 (0.45) | PTGS1PTGS2KDM4EALDH1A1HPGD | |
| SCHEMBL30108046 | 0.84 | KDM4E (0.39) | PTGS1PTGS2KDM4EALDH1A1HPGD | |
| SCHEMBL30107959 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1HPGDADORA2AADORA1 | |
| SCHEMBL30107986 | 0.84 | HSD17B10 (0.38) | PTGS1PTGS2KDM4EALDH1A1HPGD | |
| SCHEMBL30107991 | 0.84 | HSD17B10 (0.38) | PTGS1PTGS2KDM4EALDH1A1HPGD | |
| SCHEMBL30108012 | 0.83 | TSHR (0.58) | PTGS1KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL30107994 | 0.83 | PTGS1 (0.50) | PTGS1KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL30108014 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |