Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30107951 | 0.88 | PTGS1 (0.46) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL30107975 | 0.80 | L3MBTL1 (0.40) | KDM4EALDH1A1POLBRAB9AHTT | |
| SCHEMBL30107965 | 0.76 | MET (0.40) | KDM4EALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL30108028 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1HPGDMCL1TSHR | |
| SCHEMBL30108036 | 0.75 | PIM1 (0.46) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL30108039 | 0.73 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL30107968 | 0.72 | IDH1 (0.35) | ALDH1A1POLBRAB9AHTTTDP1 | |
| SCHEMBL30107959 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL30108012 | 0.70 | TSHR (0.58) | KDM4EALDH1A1HPGDPOLBRAB9A | |
| SCHEMBL30107966 | 0.69 | TSHR (0.40) | KDM4EALDH1A1MAPTPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |