Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108039 | 0.85 | ALDH1A1 (0.40) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL30107959 | 0.80 | KDM4E (0.44) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL30108037 | 0.71 | TRPC5 (0.37) | ALDH1A1KDM4EHPGDHSD17B10GLA | |
| SCHEMBL30108035 | 0.71 | NT5E (0.43) | ADORA2AADORA3ADORA2BALDH1A1KDM4E | |
| SCHEMBL30107978 | 0.71 | KDM4E (0.44) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL30107990 | 0.70 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDALOX15CASP1 | |
| SCHEMBL30108015 | 0.69 | HRH3 (0.46) | KDM4ENPC1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL30108014 | 0.69 | KDM4E (0.42) | ADORA2AADORA1ADORA3ADORA2BALDH1A1 | |
| SCHEMBL30108001 | 0.68 | KDM4E (0.33) | KDM4EHSD17B10LMNANPC1L3MBTL1 | |
| SCHEMBL12590359 | 0.68 | HRH4 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |