Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108075 | 0.88 | KDM4E (0.34) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30108077 | 0.85 | SLC6A2 (0.40) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30108071 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30108011 | 0.77 | TLR9 (0.43) | KDM4EALDH1A1GAATSHR | |
| SCHEMBL30107937 | 0.75 | HSD17B10 (0.38) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30108006 | 0.75 | CCNA2 (0.36) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30107978 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30108012 | 0.73 | TSHR (0.58) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30108046 | 0.73 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30107951 | 0.71 | PTGS1 (0.46) | KDM4EALDH1A1GAAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |