Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.33 |
| ▸ | PIM1 | P11309 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108021 | 0.88 | KDM4E (0.36) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30107960 | 0.84 | SLC6A2 (0.40) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30108077 | 0.72 | SLC6A2 (0.40) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30107972 | 0.68 | KDM4E (0.35) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30108071 | 0.66 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30108011 | 0.65 | TLR9 (0.43) | KDM4EALDH1A1GAATSHR | |
| SCHEMBL30108016 | 0.62 | CHEK2 (0.47) | HPGDCHEK2ITGB3ITGA2BKCNH2 | |
| SCHEMBL30107937 | 0.61 | HSD17B10 (0.38) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL30186215 | 0.61 | SLC6A2 (0.73) | KDM4ECHEK2ITGB3ITGA2BKCNH2 | |
| SCHEMBL4329812 | 0.59 | ITGB3 (0.49) | CHEK2ITGB3ITGA2BADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |